N-Methyl-DL-asparticacid (17833-53-3) Kaihanga - Cofttek

N-Methyl-DL-asparticacid (17833-53-3)

June 29, 2022

Ko Cofttek te kaihanga N-Methyl-DL-asparticacid (17833-53-3) pai rawa atu i Haina. Ko ta maatau wheketere he punaha whakahaere whakaputa (ISO9001 & ISO14001), me te kaha o te whakaputanga marama o 260kg.


tūnga: I roto i te Production Production
Waea: 1kg / putea, 25kg / Taramu

N-Methyl-DL-asparticacid Snga whakaritenga

ingoa: N-Methyl-DL-asparticacid
CAS: 17833-53-3
viivii 98 orau
Tātai rāpoi: C5H9NO4
Taumaha Molecular: 147.130 g / mol
Te Kaupae: 189-190 C
Ingoa matū: (2R)-2-(Methylamino)butanedioic acid
taurite: N-Methylaspartate; N-Methyl-D-aspartate; NMDA
KAUPAPA KI: HOKKHZGPKSLGJE-GSVOUGTGSA-N
Te Haurua Haurua: N / He
Haupae: Wairewa ki te wai; Ewaro; DMSO
Tikanga rokiroki: 0 - 4 C mo te wa poto (nga ra ki nga wiki), -20 C ranei mo te wa roa (marama)
Taupānga: Ko te waikawa N-methyl-D-aspartic, ko te N-methyl-D-aspartate ranei he waikawa amino e mahi ana hei agonist motuhake i te kaiwhakawhiwhi NMDA e pee ana i te mahi a te glutamate, te neurotransmitter e mahi ana i taua kaikawe.
ahua: paura White

 

He aha te N-Methyl-DL-asparticacid (17833-53-3)?

Ko te N-Methyl-DL-Aspartic Acid (NMDLA) e tohu ana i te ranunga racemic o D me L enantiomers (NMDA; NMLA). He rereke nga mahi koiora o ia enantiomer me te maha o nga momo kiko/momo. No reira, me whakaaro motuhake ia enantiomer. Ko te NMDA he neurotoxin kua akona nuitia he agonist o te kaiwhakawhiwhi NMDA me te akiaki i nga riiona roro. Kare te NMDA i te nuinga o te wa ka kitea i roto i nga kopa, ko te NMLA ka kitea noa i roto i etahi bivalves.

 

N-Methyl-DL-asparticacid (17833-53-3) painga

Ko te NMDA (N-methyl-D-aspartic acid) he agonist rongonui mo te karaehe o nga kaiwhakawhiwhi glutamate, te momo NMDA. Ko te NMDA Hangaia he mahi tino kaha mo te whakaurunga o nga mea hypothalamic me nga homoni hypophyseal i roto i nga kararehe whakangote. I tua atu, kua kitea te NMDA endogenous i roto i te kiore, kei reira he mahi ki te whakauru i te GnRH (Gonadotropin Releasing Hormone) i roto i te hypothalamus, me te LH (Luteinizing Hormone) me te PRL (Prolactin) i roto i te pituitary gland.

 

N-Methyl-DL-asparticacid (17833-53-3) Taupānga?

Ko te waikawa N-methyl-d-aspartic, ko te N-methyl-d-aspartate ranei (NMDA) he waikawa amino e mahi ana hei agonist motuhake i te kaiawhina NMDA e tohu ana i te mahi a te glutamate, te neurotransmitter e mahi ana i taua kaikawe. Kaore i te rite ki te glutamate, ko te NMDA anake te here me te whakahaere i te kaiwhiwhi NMDA, a, kaore he painga ki etahi atu kaiwhiwhi glutamate (penei mo te AMPA me te kainate). He mea tino nui nga kaiwhakawhiwhi NMDA ina kaha ana te mahi i te wa, hei tauira, te tango i te waipiro na te mea ka puta nga tohu penei i te ohooho, i etahi wa, ka hopukina epileptiform.

 

N-Methyl-DL-asparticacid paura mō te hoko(Kei hea te hoko i te paura N-Methyl-DL-asparticacid i te nuinga)

He pai ki ta maatau kamupene nga hononga roa me o taatau kiritaki na te mea e arotahi ana ki nga ratonga kiritaki me te whakarato hua nui. Mena kei te aro atu koe ki o maatau hua, he ngawari o taatau ki te whakarite i nga ota ka uru atu ki o hiahia motuhake, me to maatau tere tere mo nga whakahau ka haangai koe ki te whakamatau i a maatau hua i runga i te waa. Ka aro nui a matou ki nga ratonga taapiri. E waatea ana mo nga patai ratonga me nga korero hei tautoko i to umanga.

Ko matou he kaiwhakarato paura N-Methyl-DL-asparticacid ngaio mo etahi tau, ka tukuna e matou nga hua me te utu whakataetae, a ko o matou hua he kounga teitei me te whakamatau i nga whakamatautau motuhake, motuhake kia mohio ai he haumaru mo te kai puta noa i te ao.

 

Tohutoro

  1. "N-Methylaspartate - Whakarapopototanga Whakarato". Panui PubChem. USA: Pokapū a-Motu mo nga korero Biotechnology. 24 Pipiri 2005. Tuakiri. I tangohia i te 9 o Hanuere 2012.
  2. Watkins, JC (Noema 1962). "Ko te whakahiato o etahi waikawa amino waikawa e mau ana i te mahi neuropharmacological". Journal of Medicinal and Pharmaceutical Chemistry. 5 (6): 1187–1199.
  3. Buhusi, CV; Oprisan, SA; Buhusi, M (Aperira 2016). "Nga Karaka i roto i nga Karaka: Te Waa Ma te Kitenga Tikanga". Whakaaro o naianei i roto i nga Putaiao Whanonga. 8:207–213.